pilot scale freeze dryer for use in pharmaceutical plants

Core Features

1. Full-automatic programming control: PLC system with touch human-machine interface, customizable and savable freeze-drying programs, supports 40 temperature control parameter settings for variable/complex processes.
2. Powerful data recording: FAT32 file system with USB export; continuously saves over 3 months of operation data for batch recording and quality tracing.
3. High-precision temperature control: Silicone oil circulating temperature control, error <1°C, stable and uniform temperature for reliable process optimization.
4. Silent and efficient: Imported silent compressor and high-efficiency drying filter, low noise, long life, strong system stability.
5. Transparent visual window: High-transparency organic glass door for real-time observation of material status.
6. Cold trap split structure: Physical isolation of cold trap and drying chamber, higher water capture efficiency, reduced cross-contamination, faster drying.
7. Intelligent frost management: Automatic defrost function, reduces manual maintenance.
8. Inert gas filling interface: Nitrogen and other gases can be injected post-drying to improve product storage stability.
9. Tray structure optimization: Square stainless steel trays, regular shape, corrosion-resistant, easy material distribution and cleaning.

Performance Advantages

1. Pilot mass production support: Suitable for grams to kilograms batches, various bottle/tray specifications.
2. Flexible program settings: Adaptable for process exploration and batch verification.
3. Multi-layer temperature monitoring: Independent probe in each partition layer, real-time multi-layer curve reading for heat analysis.
4. Multiple data security mechanisms: Password management, anti-tampering, operation log for process safety and traceability.
5. Easy maintenance: Full stainless steel design, dust/corrosion resistant, easy daily cleaning and upkeep.

Working Principle

1. Pre-freezing: Shelves cool and freeze material in the drying chamber, forming stable ice crystals.
2. Sublimation drying: Under high vacuum, ice crystals sublimate directly to water vapor, rapidly captured by the cold trap.
3. Resolution drying: Further reduces combined water content, stabilizing product residual water rate.

The entire process occurs in a closed environment, avoiding microbial or external contamination, ideal for biological substances.

Application Fields

1. Pharmaceutical industry: lyophilized vaccines, powder for injection, antibiotics, celine bottle preparation.
2. Traditional Chinese medicine & natural products: dehydration and preservation of herbs and plant extracts.
3. Food industry: freeze-dried coffee, fruit/vegetable powder, seafood, health foods.
4. Life science: storage of proteins, enzymes, antibodies, cell culture media.
5. Research institutes & pilot bases: process development, validation, small batch finalization.

Cavity Types

1. Standard type chamber: Without automatic pressure plug, for tray or common container drying, suitable for products with low sealing requirements.
2. Upper pressure type chamber: Built-in automatic pressure plug device for vacuum sealing inside bottles post-lyophilization, ideal for injectables and drugs requiring high sealing/stability.