hybridization system that can handle up to twelve slides

Hybridization System

This system ensures high specificity and reproducibility for hybridization reactions by precisely controlling temperature, humidity, and time. It is an essential platform for experiments such as fluorescence in situ hybridization (FISH), in situ PCR, and RNA in situ hybridization.

Features

1. Full-color Touch Screen Control: Intuitive operation; interface supports Chinese and English switching for versatile lab use.
2. Intelligent Program Control: Stores and recalls up to 105 custom programs, supporting diverse experimental needs.
3. Precise Platform Temperature Control: Accuracy up to ±0.1 °C; efficient heating for rapid and uniform warming.
4. Automatic Humidification & Sealing: Built-in humidifier and closed lid prevent sample drying and enhance reaction efficiency.
5. Multi-tasking Parallel Processing: Processes up to 12 standard slides at once, boosting experimental throughput.
6. Power Failure Design: Recovery function allows continuation from interruption point after power is restored, avoiding data loss.
7. Intelligent Preheating & Automatic Cooling: Programmable preheating and post-experiment auto-cooling for safety and user experience.
8. Multi-mode Operation: Supports “denaturation + hybridization”, “hybridization”, “in situ PCR”, and other modes.

Core Advantages

1. High Stability & Consistency: Advanced PID temperature control technology ensures uniform temperature distribution and high reproducibility.
2. Labor-saving, High Throughput: Handles multiple samples simultaneously—reduces manual operation, ideal for batch work in medium and large labs.
3. Flexible Application Expansion: Multi-purpose compatibility with various processes and staining methods for broad research and clinical support.
4. High Degree of Automation: Intelligent logic control system minimizes operator intervention and risks.

Working Principle

1. Sample Heating & Denaturation: High temperature separates DNA double strands, preparing single strands for probe hybridization.
2. Constant Temperature Hybridization: Maintains optimal temperature and humidity for specific probe-target binding.
3. Integrated Processing: Automatically carries out denaturation, hybridization, and in situ PCR within a closed environment, minimizing interference and maximizing specificity and stability.

Application Fields

1. Medical Pathology: Tumor marker detection (e.g., HER2), chromosome abnormality analysis, pathogen localization.
2. Molecular Genetics Research: Target sequence detection and localization in gene expression and chromosome studies.
3. Clinical Molecular Diagnosis: HPV detection for cervical cancer, genetic disease screening, PGD.
4. Animal & Plant Research: RNA in situ hybridization, tissue-specific gene expression analysis.
5. Precision Medicine & Personalized Treatment: Quantitative support for drug target screening and efficacy monitoring.